NY Times Mag has an article on "superweeds", weeds resistant to herbicides, specifically Palmer amaranth.
It's a reminder that as we change our environment, our environment changes as well. Natural selection rules. The same process is going on with bacteria, as we get resistance to antibiotics.
I don't know, and haven't noticed discussion, whether the use of Crispr and the sort of science which led to the fast development of covid vaccines has any implications for our fights against resistance.