Kevin Drum had a crystal ball post--how will Paul Ryan and Clinton work together after the election. He got a lot of comments.
All I know is it's going to be interesting. One problem for the Democrats is the number of senators up for reelection in 2018, including a number from red states (Manchin, Heidtkamp, etc.). So there's a strategic choice in the Senate: either go for broke on liberal issues (assuming you can get the Dems to buy it) and sacrifice your majority in 2018; or try to preserve your majority in 2018 by dodging the more controversial issues, at the risk of aggravating the left and laying the ground for a challenge in 2020.